Conference Agenda<\/title>\n <style>\n @import url('https:\/\/fonts.googleapis.com\/css2?family=Inter:wght@400;500;600;700&family=JetBrains+Mono:wght@400;500&display=swap');\n\n \/* Reset for WordPress embedding *\/\n .conference-schedule * {\n box-sizing: border-box;\n }\n\n .conference-schedule {\n font-family: 'Inter', system-ui, sans-serif;\n color: #1a202c;\n background: transparent;\n margin: 0;\n padding: 20px 0;\n }\n\n .agenda-container {\n max-width: 100%;\n margin: 0 auto;\n padding: 0;\n background: transparent;\n border-radius: 0;\n box-shadow: none;\n }\n\n .agenda-title {\n text-align: center;\n font-size: 2.5em;\n font-weight: 700;\n background: linear-gradient(135deg, #667eea 0%, #764ba2 100%);\n background-clip: text;\n -webkit-background-clip: text;\n -webkit-text-fill-color: transparent;\n margin-bottom: 40px;\n padding-top: 10px;\n padding-bottom: 10px;\n letter-spacing: -0.02em;\n position: relative;\n line-height: 1.2;\n display: inline-block;\n width: 100%;\n 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Program<\/div>\n \n <div class=\"tabs\">\n <button class=\"tab-button active\" onclick=\"showTab('day1')\">Thursday 6th November<\/button>\n <button class=\"tab-button\" onclick=\"showTab('day2')\">Friday 7th November<\/button>\n <\/div>\n\n <div id=\"day1\" class=\"tab-content active\">\n <div class=\"timeline\">\n <div class=\"event-card\">\n <div class=\"event-time\">10:00 \u2013 10:30<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Registration<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">10:30 \u2013 10:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Welcome<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">10:40 \u2013 11:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Keynote Session \u2013 Prof. Harry Low (Imperial College, London)<\/div>\n <div class=\"event-detail\">\n <div style=\"display: flex; align-items: center; gap: 16px; margin-top: 8px;\">\n <a href=\"https:\/\/www.thelowlab.org\/hlow\" target=\"_blank\" style=\"flex-shrink: 0;\">\n <img decoding=\"async\" src=\"https:\/\/profiles.imperial.ac.uk\/h.low\/thumbnail\" alt=\"Prof. Harry Low\" style=\"width: 100px; height: 100px; border-radius: 50%; object-fit: cover; border: 2px solid #667eea; cursor: pointer; transition: border-color 0.2s;\">\n <\/a>\n <div>\n <h4 style=\"margin: 0 0 8px 0; color: #667eea; font-weight: 600; font-size: 1.1em;\">ESCRT-III-like proteins in bacteria: their role in membrane stress and repair<\/h4>\n <p style=\"margin: 0 0 8px 0; line-height: 1.6; text-align: justify;\">Membrane remodelling and repair in response to cellular stress is a fundamental requirement for all life. This process is mediated by protein families including Vipp1 (cyanobacteria), PspA (bacteria), and ESCRT-III (eukaryotes). In this talk, we will explore the structural and evolutionary evidence that shows these proteins to be homologous, suggesting a common origin predating the last universal common ancestor (LUCA). Cryo-EM and atomic force microscopy (AFM) are combined to reveal the remarkable capabilities of Vipp1 to build highly dynamic structures including, rings, sheets and spirals around membrane. Collectively, our data suggests a mechanism for Vipp1-mediated membrane stress response and repair in cyanobacteria and chloroplasts. It also has implication for how other homologues such as PspA, or the antibiotic induced LiaH, mitigate membrane stress across bacteria.<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">11:40 \u2013 12:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 1 – <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Natalie Tatum<br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>11:40 \u2013 12:00<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Maria Fando<\/strong> <span class=\"title-italic\">CCP4 general presentation<\/span><\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>12:00 \u2013 12:20<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr August Silale<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">A molecular motor that energizes transport across the bacterial outer membrane<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>12:20 \u2013 12:40<\/strong><\/div>\n <div class=\"talk-title\"><strong>William Houppy<\/strong> – <span class=\"title-italic\">Northumbria University (Newcastle)<\/span> — “<span class=\"title-italic\">QM\/MM Study of Alginate Lyase Mechanisms (with the wrong substrate)<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">12:40 \u2013 13:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\ud83c\udf7d\ufe0f Lunch<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">13:40 \u2013 15:10<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 2 – <em class=\"session-format\">(Diamond: 20 min talk, 10 min Q&A)<\/em> <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Eleanor Boardman <br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>13:40 \u2013 14:10<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Adam Crawshaw<\/strong> – <span class=\"title-italic\">Diamond Light Source<\/span> — “<span class=\"title-italic\">X-ray diffraction from protein microcrystals at Diamond<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>14:10 \u2013 14:30<\/strong><\/div>\n <div class=\"talk-title\"><strong>\u00c9il\u00eds McClay<\/strong> – <span class=\"title-italic\">University of Glasgow<\/span> — “<span class=\"title-italic\">Exploring the Human Proteasome Regulation by Divalent Cations<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>14:30 \u2013 14:50<\/strong><\/div>\n <div class=\"talk-title\"><strong>Joshua Ratliffe<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">Investigating Oxidation-Induced Formation and Structure of Disulphide-Linked Conjugates by p62\/SQSTM1<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>14:50 \u2013 15:10<\/strong><\/div>\n <div class=\"talk-title\"><strong>Lucy Schofield<\/strong> – <span class=\"title-italic\">University of York<\/span> — “<span class=\"title-italic\">Structural and Conformational Analysis of Post-Translational Modifications in the Protein Data Bank<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">15:10 \u2013 15:30<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\u2615 Coffee<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">15:30 \u2013 17:00<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 3 – <em class=\"session-format\">(Diamond: 20 min talk, 10 min Q&A)<\/em> <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Nahoum Anthony<br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>15:30 \u2013 16:00<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Abbey Telfer<\/strong> – <span class=\"title-italic\">Diamond Light Source<\/span> — “<span class=\"title-italic\">Exploring time resolved serial crystallography for structural biology at synchrotrons and XFELs<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>16:00 \u2013 16:20<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Jennifer Miles<\/strong> – <span class=\"title-italic\">University of Leeds<\/span> — “<span class=\"title-italic\">Using motif scaffolding to create designed binders against Aurora-A kinase<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>16:20 \u2013 16:40<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Thomas McCorvie\n<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">TBA<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>16:40 \u2013 17:00<\/strong><\/div>\n <div class=\"talk-title\"><strong>William Hall<\/strong> – <span class=\"title-italic\">Durham University<\/span> — “<span class=\"title-italic\">A programmable crosslinker for modular assembly and functionalisation of TRAP protein cages<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">18:00 \u2013 20:00<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\ud83c\udf7d\ufe0f Dinner \/ Social<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n\n <div id=\"day2\" class=\"tab-content\">\n <div class=\"timeline\">\n <div class=\"event-card\">\n <div class=\"event-time\">09:00 \u2013 10:30<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 4 – <em class=\"session-format\">(Diamond: 20 min talk, 10 min Q&A)<\/em> <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Javier Abellon Ruiz<br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>09:00 \u2013 09:30<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Christian Orr<\/strong> – <span class=\"title-italic\">Diamond Light Source<\/span> — “<span class=\"title-italic\">Using long-wavelength X-ray diffraction to localise light atoms in macromolecular crystals<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>09:30 \u2013 09:50<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Francesca Mazzotta<\/strong> – <span class=\"title-italic\">Max Planck Institute for Polymer Research<\/span> — “<span class=\"title-italic\">LEGO-like peptide assembly if honeycomb multichannel nanofibrils<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>09:50 \u2013 10:10<\/strong><\/div>\n <div class=\"talk-title\"><strong>Robbie Burton<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">Crystallographic Fragment Mapping of Cyclin H: Unravelling Transcriptional and Cell Cycle Regulation<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>10:10 \u2013 10:30<\/strong><\/div>\n <div class=\"talk-title\"><strong>Abykhair Muhammad<\/strong> – <span class=\"title-italic\">Durham University<\/span> — “<span class=\"title-italic\">Understanding gold-coordinated TRAP-cage interaction using computationally designed protein, mono-TRAP<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">10:30 \u2013 11:20<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\u2615 Coffee & Posters<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">11:20 \u2013 12:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 5 – <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Kenneth Tan<br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>11:20 \u2013 11:40<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Jonathon Liston<\/strong> – <span class=\"title-italic\">Durham University<\/span> — “<span class=\"title-italic\">CryoMPNN: training artificial intelligence for flexible proteins<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>11:40 \u2013 12:00<\/strong><\/div>\n <div class=\"talk-title\"><strong>Katie McLennan<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">CRISPR-mediated tagging of endogenous proteins to enable structural biology<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>12:20 \u2013 12:40<\/strong><\/div>\n <div class=\"talk-title\"><strong>Isabel Cormack<\/strong> – <span class=\"title-italic\">Durham University<\/span> — “<span class=\"title-italic\">Structure, Function, and Applications of Two Phage Recombinases from Extreme Environments<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">12:40 \u2013 13:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\ud83c\udf7d\ufe0f Lunch<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">13:40 \u2013 15:10<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 6 – <em class=\"session-format\">(Diamond: 20 min talk, 10 min Q&A)<\/em> <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Rowan Walters <br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>13:40 \u2013 14:10<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Megan Lambert<\/strong> – <span class=\"title-italic\">Diamond Light Source<\/span> — “<span class=\"title-italic\">Room-Temperature Fragment-based Screening at VMXi: Optimisation of a High-Throughput Experiment<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>14:10 \u2013 14:30<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Alexander Konstrantinov<\/strong> – <span class=\"title-italic\">UKRI, STFC, Research Complex at Harwell, CCP-EM\/CCP4<\/span> — “<span class=\"title-italic\">Bayesian Optimisation of Macromolecular Crystallographic Model Refinement<\/span>”<\/div>\n <\/div>\n \n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>14:30 \u2013 14:50<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Paola Lanzoni-Mangutchi<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">Giving GALK1 a stab on the back: the study of GALK1 inactivation through its allosteric site<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">14:50 \u2013 15:30<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\u2615 Coffee<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">15:30 \u2013 16:30<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Careers Panel<\/div>\n <div class=\"event-detail\">\n <strong>Lead:<\/strong> Victoria Burge<br>\n\n <div class=\"talk-schedule\">\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Academic Professor:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Prof Paul Race<\/strong> (Newcastle University)<\/div>\n <\/div>\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Industry Team Leader:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Dr Claire Jennings<\/strong> (CPI-UK – Darlington)<\/div>\n <\/div>\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Facility Manager:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Dr Arnaud Basle<\/strong> (Newcastle University)<\/div>\n <\/div>\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Beamline Scientist:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Dr Adam Crawshaw<\/strong> (DLS)<\/div>\n <\/div>\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Research Associate:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Dr Paul Bond<\/strong> (University of York)<\/div>\n <\/div>\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Software Engineer:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Dr Maria Fando<\/strong> (STFC – Oxford)<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">16:30 \u2013 16:45<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Prizes & Close<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n\n <script>\n function showTab(tabId) {\n \/\/ Hide all tab contents\n const tabContents = document.querySelectorAll('.tab-content');\n tabContents.forEach(content => {\n content.classList.remove('active');\n });\n\n \/\/ Remove active class from all tab buttons\n const tabButtons = document.querySelectorAll('.tab-button');\n tabButtons.forEach(button => {\n button.classList.remove('active');\n });\n\n \/\/ Show selected tab content\n document.getElementById(tabId).classList.add('active');\n\n \/\/ Add active class to clicked button\n event.target.classList.add('active');\n }\n <\/script>\n<\/body>\n<\/html>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Conference Agenda Conference Program Thursday 6th November Friday 7th November 10:00 \u2013 10:30 Registration 10:30 \u2013 10:40 Welcome 10:40 \u2013 11:40 Keynote Session \u2013 Prof. Harry Low (Imperial College, London) ESCRT-III-like proteins in bacteria: their role in membrane stress and repair Membrane remodelling and repair in response to cellular stress is a fundamental requirement for … <\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-923","page","type-page","status-publish","hentry","entry"],"yoast_head":"\n<title>What's On - CCP4 Northern Conference 2025<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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{"id":923,"date":"2025-03-14T09:29:32","date_gmt":"2025-03-14T09:29:32","guid":{"rendered":"https:\/\/nusbf.ncl.ac.uk\/ccp4-northern-conference-2025-archive\/?page_id=923"},"modified":"2025-11-04T22:05:26","modified_gmt":"2025-11-04T22:05:26","slug":"indicative-programme","status":"publish","type":"page","link":"https:\/\/nusbf.ncl.ac.uk\/ccp4-northern-conference-2025\/indicative-programme\/","title":{"rendered":"What’s On"},"content":{"rendered":"\n

<\/p>\n\n\n\n

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class=\"agenda-title\">Conference Program<\/div>\n \n <div class=\"tabs\">\n <button class=\"tab-button active\" onclick=\"showTab('day1')\">Thursday 6th November<\/button>\n <button class=\"tab-button\" onclick=\"showTab('day2')\">Friday 7th November<\/button>\n <\/div>\n\n <div id=\"day1\" class=\"tab-content active\">\n <div class=\"timeline\">\n <div class=\"event-card\">\n <div class=\"event-time\">10:00 \u2013 10:30<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Registration<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">10:30 \u2013 10:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Welcome<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">10:40 \u2013 11:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Keynote Session \u2013 Prof. Harry Low (Imperial College, London)<\/div>\n <div class=\"event-detail\">\n <div style=\"display: flex; align-items: center; gap: 16px; margin-top: 8px;\">\n <a href=\"https:\/\/www.thelowlab.org\/hlow\" target=\"_blank\" style=\"flex-shrink: 0;\">\n <img decoding=\"async\" src=\"https:\/\/profiles.imperial.ac.uk\/h.low\/thumbnail\" alt=\"Prof. Harry Low\" style=\"width: 100px; height: 100px; border-radius: 50%; object-fit: cover; border: 2px solid #667eea; cursor: pointer; transition: border-color 0.2s;\">\n <\/a>\n <div>\n <h4 style=\"margin: 0 0 8px 0; color: #667eea; font-weight: 600; font-size: 1.1em;\">ESCRT-III-like proteins in bacteria: their role in membrane stress and repair<\/h4>\n <p style=\"margin: 0 0 8px 0; line-height: 1.6; text-align: justify;\">Membrane remodelling and repair in response to cellular stress is a fundamental requirement for all life. This process is mediated by protein families including Vipp1 (cyanobacteria), PspA (bacteria), and ESCRT-III (eukaryotes). In this talk, we will explore the structural and evolutionary evidence that shows these proteins to be homologous, suggesting a common origin predating the last universal common ancestor (LUCA). Cryo-EM and atomic force microscopy (AFM) are combined to reveal the remarkable capabilities of Vipp1 to build highly dynamic structures including, rings, sheets and spirals around membrane. Collectively, our data suggests a mechanism for Vipp1-mediated membrane stress response and repair in cyanobacteria and chloroplasts. It also has implication for how other homologues such as PspA, or the antibiotic induced LiaH, mitigate membrane stress across bacteria.<\/p>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">11:40 \u2013 12:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 1 – <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Natalie Tatum<br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>11:40 \u2013 12:00<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Maria Fando<\/strong> <span class=\"title-italic\">CCP4 general presentation<\/span><\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>12:00 \u2013 12:20<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr August Silale<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">A molecular motor that energizes transport across the bacterial outer membrane<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>12:20 \u2013 12:40<\/strong><\/div>\n <div class=\"talk-title\"><strong>William Houppy<\/strong> – <span class=\"title-italic\">Northumbria University (Newcastle)<\/span> — “<span class=\"title-italic\">QM\/MM Study of Alginate Lyase Mechanisms (with the wrong substrate)<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">12:40 \u2013 13:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\ud83c\udf7d\ufe0f Lunch<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">13:40 \u2013 15:10<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 2 – <em class=\"session-format\">(Diamond: 20 min talk, 10 min Q&A)<\/em> <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Eleanor Boardman <br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>13:40 \u2013 14:10<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Adam Crawshaw<\/strong> – <span class=\"title-italic\">Diamond Light Source<\/span> — “<span class=\"title-italic\">X-ray diffraction from protein microcrystals at Diamond<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>14:10 \u2013 14:30<\/strong><\/div>\n <div class=\"talk-title\"><strong>\u00c9il\u00eds McClay<\/strong> – <span class=\"title-italic\">University of Glasgow<\/span> — “<span class=\"title-italic\">Exploring the Human Proteasome Regulation by Divalent Cations<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>14:30 \u2013 14:50<\/strong><\/div>\n <div class=\"talk-title\"><strong>Joshua Ratliffe<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">Investigating Oxidation-Induced Formation and Structure of Disulphide-Linked Conjugates by p62\/SQSTM1<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>14:50 \u2013 15:10<\/strong><\/div>\n <div class=\"talk-title\"><strong>Lucy Schofield<\/strong> – <span class=\"title-italic\">University of York<\/span> — “<span class=\"title-italic\">Structural and Conformational Analysis of Post-Translational Modifications in the Protein Data Bank<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">15:10 \u2013 15:30<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\u2615 Coffee<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">15:30 \u2013 17:00<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 3 – <em class=\"session-format\">(Diamond: 20 min talk, 10 min Q&A)<\/em> <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Nahoum Anthony<br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>15:30 \u2013 16:00<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Abbey Telfer<\/strong> – <span class=\"title-italic\">Diamond Light Source<\/span> — “<span class=\"title-italic\">Exploring time resolved serial crystallography for structural biology at synchrotrons and XFELs<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>16:00 \u2013 16:20<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Jennifer Miles<\/strong> – <span class=\"title-italic\">University of Leeds<\/span> — “<span class=\"title-italic\">Using motif scaffolding to create designed binders against Aurora-A kinase<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>16:20 \u2013 16:40<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Thomas McCorvie\n<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">TBA<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>16:40 \u2013 17:00<\/strong><\/div>\n <div class=\"talk-title\"><strong>William Hall<\/strong> – <span class=\"title-italic\">Durham University<\/span> — “<span class=\"title-italic\">A programmable crosslinker for modular assembly and functionalisation of TRAP protein cages<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">18:00 \u2013 20:00<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\ud83c\udf7d\ufe0f Dinner \/ Social<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n\n <div id=\"day2\" class=\"tab-content\">\n <div class=\"timeline\">\n <div class=\"event-card\">\n <div class=\"event-time\">09:00 \u2013 10:30<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 4 – <em class=\"session-format\">(Diamond: 20 min talk, 10 min Q&A)<\/em> <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Javier Abellon Ruiz<br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>09:00 \u2013 09:30<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Christian Orr<\/strong> – <span class=\"title-italic\">Diamond Light Source<\/span> — “<span class=\"title-italic\">Using long-wavelength X-ray diffraction to localise light atoms in macromolecular crystals<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>09:30 \u2013 09:50<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Francesca Mazzotta<\/strong> – <span class=\"title-italic\">Max Planck Institute for Polymer Research<\/span> — “<span class=\"title-italic\">LEGO-like peptide assembly if honeycomb multichannel nanofibrils<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>09:50 \u2013 10:10<\/strong><\/div>\n <div class=\"talk-title\"><strong>Robbie Burton<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">Crystallographic Fragment Mapping of Cyclin H: Unravelling Transcriptional and Cell Cycle Regulation<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>10:10 \u2013 10:30<\/strong><\/div>\n <div class=\"talk-title\"><strong>Abykhair Muhammad<\/strong> – <span class=\"title-italic\">Durham University<\/span> — “<span class=\"title-italic\">Understanding gold-coordinated TRAP-cage interaction using computationally designed protein, mono-TRAP<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">10:30 \u2013 11:20<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\u2615 Coffee & Posters<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">11:20 \u2013 12:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 5 – <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Kenneth Tan<br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>11:20 \u2013 11:40<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Jonathon Liston<\/strong> – <span class=\"title-italic\">Durham University<\/span> — “<span class=\"title-italic\">CryoMPNN: training artificial intelligence for flexible proteins<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>11:40 \u2013 12:00<\/strong><\/div>\n <div class=\"talk-title\"><strong>Katie McLennan<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">CRISPR-mediated tagging of endogenous proteins to enable structural biology<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>12:20 \u2013 12:40<\/strong><\/div>\n <div class=\"talk-title\"><strong>Isabel Cormack<\/strong> – <span class=\"title-italic\">Durham University<\/span> — “<span class=\"title-italic\">Structure, Function, and Applications of Two Phage Recombinases from Extreme Environments<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">12:40 \u2013 13:40<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\ud83c\udf7d\ufe0f Lunch<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">13:40 \u2013 15:10<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Talk Session 6 – <em class=\"session-format\">(Diamond: 20 min talk, 10 min Q&A)<\/em> <em class=\"session-format\">(15 min talk, 5 min Q&A)<\/em><\/div>\n <div class=\"event-detail\">\n <strong>Chair:<\/strong> Dr Rowan Walters <br>\n <div class=\"talk-schedule\">\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>13:40 \u2013 14:10<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Megan Lambert<\/strong> – <span class=\"title-italic\">Diamond Light Source<\/span> — “<span class=\"title-italic\">Room-Temperature Fragment-based Screening at VMXi: Optimisation of a High-Throughput Experiment<\/span>”<\/div>\n <\/div>\n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>14:10 \u2013 14:30<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Alexander Konstrantinov<\/strong> – <span class=\"title-italic\">UKRI, STFC, Research Complex at Harwell, CCP-EM\/CCP4<\/span> — “<span class=\"title-italic\">Bayesian Optimisation of Macromolecular Crystallographic Model Refinement<\/span>”<\/div>\n <\/div>\n \n <div class=\"talk-item\">\n <div class=\"talk-time\"><strong>14:30 \u2013 14:50<\/strong><\/div>\n <div class=\"talk-title\"><strong>Dr Paola Lanzoni-Mangutchi<\/strong> – <span class=\"title-italic\">Newcastle University<\/span> — “<span class=\"title-italic\">Giving GALK1 a stab on the back: the study of GALK1 inactivation through its allosteric site<\/span>”<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card break-card\">\n <div class=\"event-time\">14:50 \u2013 15:30<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">\u2615 Coffee<\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">15:30 \u2013 16:30<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Careers Panel<\/div>\n <div class=\"event-detail\">\n <strong>Lead:<\/strong> Victoria Burge<br>\n\n <div class=\"talk-schedule\">\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Academic Professor:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Prof Paul Race<\/strong> (Newcastle University)<\/div>\n <\/div>\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Industry Team Leader:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Dr Claire Jennings<\/strong> (CPI-UK – Darlington)<\/div>\n <\/div>\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Facility Manager:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Dr Arnaud Basle<\/strong> (Newcastle University)<\/div>\n <\/div>\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Beamline Scientist:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Dr Adam Crawshaw<\/strong> (DLS)<\/div>\n <\/div>\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Research Associate:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Dr Paul Bond<\/strong> (University of York)<\/div>\n <\/div>\n <div class=\"panel-item\">\n <div class=\"panel-role\"><strong>Software Engineer:<\/strong><\/div>\n <div class=\"panel-person\"><strong>Dr Maria Fando<\/strong> (STFC – Oxford)<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <div class=\"event-card\">\n <div class=\"event-time\">16:30 \u2013 16:45<\/div>\n <div class=\"event-content\">\n <div class=\"event-title\">Prizes & Close<\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n\n <script>\n function showTab(tabId) {\n \/\/ Hide all tab contents\n const tabContents = document.querySelectorAll('.tab-content');\n tabContents.forEach(content => {\n content.classList.remove('active');\n });\n\n \/\/ Remove active class from all tab buttons\n const tabButtons = document.querySelectorAll('.tab-button');\n tabButtons.forEach(button => {\n button.classList.remove('active');\n });\n\n \/\/ Show selected tab content\n document.getElementById(tabId).classList.add('active');\n\n \/\/ Add active class to clicked button\n event.target.classList.add('active');\n }\n <\/script>\n<\/body>\n<\/html>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Conference Agenda Conference Program Thursday 6th November Friday 7th November 10:00 \u2013 10:30 Registration 10:30 \u2013 10:40 Welcome 10:40 \u2013 11:40 Keynote Session \u2013 Prof. Harry Low (Imperial College, London) ESCRT-III-like proteins in bacteria: their role in membrane stress and repair Membrane remodelling and repair in response to cellular stress is a fundamental requirement for … <\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-923","page","type-page","status-publish","hentry","entry"],"yoast_head":"\n<title>What's On - CCP4 Northern Conference 2025<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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